The Anti-Inflammatory Activity of Nigella sativa
Balm Sticks
http://repository.uhamka.ac.id/614/
Nigella sativa oil has been known to have potent anti-inflammatory activity. This research
aimed to determine the anti-inflammation activity of Nigella sativa oil in a simple balm stick by topical
application. The activity was checked using two methods: carrageenan-induced paw oedema and
granuloma pouch on rats. The results showed that balm sticks which contained 10% Nigella sativa
could overcome both acute and sub-acute inflammation showing by high oedema inhibition (60.64%),
low leucocytes count (43.55% lower than control) as well as a notable TNF-� concentration (50%
lower than control) on the inflamed area. In conclusion, topical application of a Nigella sativa balm
stick was effective for both acute and sub-acute forms of inflammation.
